Article

Sikder, Suchandan, Pierce, Doris, Sarkar, Eti R., McHugh, Connor, Quinlan, Kate G.R., Giacomin, Paul, and Loukas, Alex (2024) Regulation of host metabolic health by parasitic helminths. Trends in Parasitology, 40 (5). pp. 386-400.

Jordan, Margaret A., Gresle, Melissa M., Gemiarto, Adrian T., Stanley, Dragana, Smith, Letitia D., Laverick, Louise, Spelman, Tim, Stankovich, Jim, Willson, Annie M.L., Dinh, Xuyen T., Johnson, Laura, Robertson, Kylie, Reid, Christopher A.R., Field, Judith, Butzkueven, Helmut, and Baxter, Alan G. (2024) Transcriptional network analysis of peripheral blood leukocyte subsets in multiple sclerosis identifies a pathogenic role for a cytotoxicity‐associated gene network in myeloid cells. Immunology & Cell Biology. (In Press)

Wassmer, Samuel C., de Koning-ward, Tania F., Grau, Georges E.R., and Pai, Saparna (2024) Unravelling mysteries at the perivascular space: a new rationale for cerebral malaria pathogenesis. Trends in Parasitology, 40 (1). pp. 28-44.

Valencia-Hernandez, Ana Maria, Zillinger, Thomas, Ge, Zhengyu, Tan, Peck S., Cozijnsen, Anton, Mcfadden, Geoffrey I., Lahoud, Mireille H., Caminsch, Irina, Barchet, Winfried, Heath, William R., and Fernandez-Ruiz, Daniel (2023) Complexing CpG adjuvants with cationic liposomes enhances vaccine-induced formation of liver TRM cells. Vaccine, 41 (5). pp. 1094-1107.

Vanderven, Hillary A., and Kent, Stephen J. (2023) Fc-mediated functions and the treatment of severe respiratory viral infections with passive immunotherapy – a balancing act. Frontiers in Immunology, 14. 1307398.

Redden, Patricia, Parker, Kaitland, Henderson, Sinead, Fourie, Phillip, Agnew, Linda, Stenos, John, Graves, Stephen, Govan, Brenda, Norton, Robert, and Ketheesan, Natkunam (2023) Q fever - immune responses and novel vaccine strategies. Future Microbiology, 18 (16). pp. 1185-1196.

Vanderven, Hillary, Wentworth, Deborah N., Han, Win Min, Peck, Heidi, Barr, Ian G., Davey, Richard T., Beigel, John H., Dwyer, Dominic E., Jain, Mamta K., Angus, Brian, Brandt, Christian T., Mykietiuk, Analia, Law, Matthew G., Neaton, James D., and Kent, Stephen J. (2023) Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza. JCI Insight, 8 (14). e167464.

Silva, Marta G., Bastos, Reginaldo G., Laughery, Jacob M., Alzan, Heba F., Rathinasamy, Vignesh A., Cooke, Brian M., and Suarez, Carlos E. (2023) Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks. NPJ Vaccines, 8. 140.

Nisa, Annuurun, Kipper, Franciele C., Panigrahy, Dipak, Tiwari, Sangeeta, Kupz, Andreas, and Subbian, Selvakumar (2022) Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection. American Journal of Physiology: cell physiology, 323 (5). C1444-C1474.

Bastos, Reginaldo G., Alzan, Heba F., Rathinasamy, Vignesh A., Cooke, Brian M., Dellagostin, Odir A., Barletta, Raúl G., and Suarez, Carlos E. (2022) Harnessing Mycobacterium bovis BCG Trained Immunity to Control Human and Bovine Babesiosis. Vaccines, 10 (1). 123.

Kristensen, Anne B., Wragg, Kathleen, Vanderven, Hillary, Lee, Wen Shi, Silvers, Julie, Kent, Helen E., Grant, Michael D., Kelleher, Anthony D., Juno, Jennifer A., Kent, Stephen J., and Parsons, Matthew S. (2022) Phenotypic and functional characteristics of highly differentiated CD57 +NKG2C + NK cells in HIV-1- infected individuals. Clinical and Experimental Immunology, 210 (2). pp. 163-174.

Vanderven, Hillary A., Esterbauer, Robyn, Jegaskanda, Sinthujan, Tan, Hyon‐Xhi, Wheatley, Adam K., and Kent, Stephen J. (2022) Poor protective potential of influenza nucleoprotein antibodies despite wide prevalence. Immunology and Cell Biology, 100 (1). pp. 49-60.

Flores-Valdez, Mario Alberto, Kupz, Andreas, and Subbian, Selvakumar (2022) Recent Developments in Mycobacteria-Based Live Attenuated Vaccine Candidates for Tuberculosis. Biomedicines, 10 (11). 2749.

Miles, John, Watkins, Thomas, Darko, Sam, Wijaya, Kuatrinnus, Cooper, Martha, Ransier, Amy, Waardenberg, Ashley, Amante, Fiona, Mccarthy, James, Price, David, Burrows, Scott, Doolan, Denise, Field, Matt, and Douek, Daniel (2022) T cell differentiation and lineage choice are determined by the TCR. FASEB Journal, 36 (S1).

Browne, Daniel J., Kelly, Ashton M., Brady, Jamie L., and Doolan, Denise L. (2022) A high-throughput screening RT-qPCR assay for quantifying surrogate markers of immunity from PBMCs. Frontiers in Immunology, 13. 962220.

Bjerkan, Louise, Visweswaran, Ganesh Ram R., Gudjonsson, Arnar, Labbé, Geneviève M., Quinkert, Doris, Pattinson, David J., Spång, Heidi C.L., Draper, Simon J., Bogen, Bjarne, and Braathen, Ranveig (2021) APC-targeted DNA vaccination against reticulocyte-binding protein homolog 5 induces plasmodium falciparum-specific neutralizing Antibodies and T Cell Responses. Frontiers in Immunology, 12. 720550.

Smith, Nicholas C., Goulart, Cibelly, Hayward, Jenni A., Kupz, Andreas, Miller, Catherine M., and van Dooren, Giel C. (2021) Control of human toxoplasmosis. International Journal for Parasitology, 51 (2-3). pp. 95-121.

Wijeyesinghe1, Sathi, Beura, Lalit K., Pierson, Mark J., Stolley, Michael J., Adam, Omar A., Ruscher, Roland, Steinert, Elizabeth M., Rosato, Pamela C., Vezys, Vaiva, and Masopust, David (2021) Expansible residence decentralizes immune homeostasis. Nature, 592. pp. 457-462.

Pearson, Mark S., Tedla, Bemnet A., Mekonnen, Gebeyaw G., Proietti, Carla, Becker, Luke, Nakajima, Rie, Jasinskas, Al, Doolan, Denise L., Amoah, Abena S., Knopp, Stefanie, Rollinson, David, Ali, Said M., Kabole, Fatma, Hokke, Cornelis H., Adegnika, Akim A., Field, Matt A., van Dam, Govert, Corstjens, Paul L.A.M., Mduluza, Takafira, Mutapi, Francisca, Oeuvray, Claude, Greco, Beatrice, Chaiyadet, Sujittra, Laha, Thewarach, Cai, Pengfei, McManus, Donald P., Bottazzi, Maria Elena, Felgner, Philip L., Sotillo, Javier, and Loukas, Alex (2021) Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study. The Lancet Microbe, 2 (11). e617-e626.

Lee, S. Thera, Georgiev, Hristo, Breed, Elise R., Ruscher, Roland, and Hogquist, Kristin A. (2021) MHC Class I on murine hematopoietic APC selects Type A IEL precursors in the thymus. European Journal of Immunology, 51 (5). pp. 1080-1088.

Qin, Jim, Michael, Lovelace D., Andrew, Mitchell J., de Koning-ward, Tania, Grau, Georges E.R., and Pai, Saparna (2021) Perivascular macrophages create an intravascular niche for CD8 + T cell localisation prior to the onset of fatal experimental cerebral malaria. Clinical and Translational Immunology, 10 (4). e1273.

Buitrago, Geraldine, Pickering, Darren, Ruscher, Roland, Cobos Caceres, Claudia, Jones, Linda, Cooper, Martha, Van Waardenberg, Ashley, Ryan, Stephanie, Miles, Kim, Field, Matthew, Dredge, Keith, Daly, Norelle L., Giacomin, Paul R., and Loukas, Alex (2021) A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis. Translational Research, 232. pp. 88-102.

Dobaño, Carlota, Bardají, Azucena, Kochar, Swati, Kochar, Sanjay K., Padilla, Norma, López, Marta, Unger, Holger W., Ome-Kaius, Maria, Castellanos, Maria Eugenia, Arévalo-Herrera, Myriam, Hans, Dhiraj, Martínez-espinosa, Flor E., Bôtto-Menezes, Camila, Malheiros, Adriana, Desai, Meghna, Casellas, Aina, Chitnis, Chetan E., Rogerson, Stephen, Mueller, Ivo, Menéndez, Clara, and Requena, Pilar (2020) Blood cytokine, chemokine and growth factor profiling in a cohort of pregnant women from tropical countries. Cytokine, 125. 154818. pp. 1-11.

Holz, Lauren E., Chua, Yu Cheng, de Menezes, Maria N., Anderson, Regan J., Draper, Sarah L., Compton, Benjamin J., Chan, Susanna T.S., Mathew, Juby, Li, Jasmine, Kedzierski, Lukasz, Wang, Zhongfang, Beattie, Lynette, Enders, Matthias H., Ghilas, Sonia, May, Rose, Steiner, Thiago M., Lange, Joshua, Fernandez-Ruiz, Daniel, Valencia-Hernandez, Ana Maria, Osmond, Taryn L., Farrand, Kathryn J., Seneviratna, Rebecca, Almeida, Catarina F., Tullett, Kirsteen M., Bertolino, Patrick, Bowen, David G., Cozijnsen, Anton, Mollard, Vanessa, Mcfadden, Geoffrey I., Caminschi, Irina, Lahoud, Mireille, Kedzierska, Katherine, Turner, Stephen J., Godfrey, Dale I., Hermans, Ian F., Painter, Gavin F., and Heath, William R. (2020) Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria. Science Immunology, 5 (48). eaaz8035.

Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E., Ladell, Kristin, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A., Tunger, Antje, Schmitz, Marc, Miles, John, Lahoud, Mireille H., and Radford, Kristen J. (2020) Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells. Clinical and Translational Immunology, 9 (6). e1141.

Ruscher, Roland, and Giacomin, Paul (2020) IL-17A moonlighting in lung type 2 immunity. Mucosal Immunology, 13. pp. 849-851.

Ruscher, Roland, Lee, S. Thera, Salgado, Oscar C., Breed, Elise R., Osum, Sara H., and Hogquist, Kristin A. (2020) Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny. Journal of Experimental Medicine, 217 (8). e20192336.

Valencia-Hernandez, Ana Maria, Ng, Wei Yi, Ghazanfari, Nazanin, Ghilas, Sonia, de Menezes, Maria N., Holz, Lauren E., Huang, Cheng, English, Kieran, Nuang, Myo, Tan, Peck Szee, Tullett, Kirsteen M., Steiner, Thiago M., Enders, Matthias H., Beattie, Lynette, Chua, Yu Cheng, Jones, Claerwen M., Cozijnsen, Anton, Mollard, Vanessa, Cai, Yeping, Bowen, David G., Purcell, Anthony W., La Gruta, Nicole L., Villadangos, Jose A., De Koning-ward, Tania, Barry, Alyssa E., Barchet, Winfried, Cockburn, Ian A., Mcfadden, Geoffrey I., Gras, Stephanie, Lahoud, Mireille H., Bertolino, Patrick, Schittenhelm, Ralf B., Caminschi, Irina, Heath, William R., and Fernandez-Ruiz, Daniel (2020) A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice. Cell Host & Microbe, 27 (6). 950-962.e7.

Ghilas, Sonia, Valencia-Hernandez, Ana Maria, Enders, Matthias H., Heath, William R., and Fernandez-Ruiz, Daniel (2020) Resident memory t cells and their role within the liver. International Journal of Molecular Sciences, 21 (22). 8565.

Habel, Jennifer H., Nguyen, Thi H.O., van de Sandt, Carolien E., Juno, Jennifer A., Chaurasia, Priyanka, Wragg, Kathleen, Koutsakos, Marios, Hensen, Luca, Jia, Xiaoxiao, Chua, Brendon, Zhang, Wuji, Tan, Hyon-Xhi, Flanagan, Katie L., Doolan, Denise L., Torresi, Joseph, Chen, Weisan, Wakim, Linda M., Cheng, Allen C., Doherty, Peter C., Petersen, Jan, Rossjohn, Jamie, Wheatley, Adam K., Kent, Stephen J., Rowntree, Louise C., and Kedzierska, Katherine (2020) Suboptimal SARS-CoV-2-specific CD8(+) T cell response associated with the prominent HLA-A*02:01 phenotype. Proceedings of the National Academy of Sciences of the United States of America, 117 (39). pp. 24384-24391.

Kaushansky, Alexis, Sibley, Carol, McFadden, Geoff, Charman, Susan, Doolan, Denise, Good, Michael, Flannery, Erika, Healer, Julie, Duffy, Michael, Taylor, Terrie, Craig, Alister, Tilley, Leann, and Gilson, Paul (2020) Trends Talk MAM 2020: growing strong on the 20th anniversary. Trends in Parasitology, 36 (6). pp. 487-494.

Browne, Daniel J., Brady, Jamie L., Van Waardenberg, Ashley J., Loiseau, Claire, and Doolan, Denise L. (2020) An analytically and diagnostically sensitive RNA extraction and RT-qPCR protocol for peripheral blood mononuclear cells. Frontiers in Immunology, 11. 402.

Loiseau, Claire, Doumbo, Ogobara K, Traore, Boubacar, Brady, Jamie L., Proietti, Carla, de Sousa, Katrina P., Crompton, Peter D., and Doolan, Denise L. (2020) A novel population of memory-activated natural killer cells associated with low parasitaemia in Plasmodium falciparum-exposed sickle-cell trait children. Clinical & Translational Immunology, 9 (4). 1125.

Pattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P.J., and Doolan, Denise L. (2019) Chimeric murine polyomavirus virus-like particles induce Plasmodium antigen-specific CD8+ T cell and antibody responses. Frontiers in Cellular and Infection Microbiology, 9. 215.

Ruscher, Roland, and Hogquist, Kristin A. (2019) Development, ontogeny, and maintenance of TCRab+ CD8aa IEL. Current Opinion in Immunology, 58. pp. 83-88.

Joseph, Hayley, Eriksson, Emily, and Schofield, Louis (2019) Early suppression of B cell immune responses by low doses of chloroquine and pyrimethamine: implications for studying immunity in malaria. Parasitology Research, 118 (6). pp. 1987-1992.

Swaminathan, Ashwin, Harrison, Simone L., Ketheesan, Natkunam, van den Boogaard, Christel H.A., Dear, Keith, Allen, Martin, Hart, Prue H., Cook, Matthew, and Lucas, Robyn M. (2019) Exposure to solar UVR suppresses cell-mediated immunization responses in humans: the Australian Ultraviolet Radiation and Immunity Study. Journal of Investigative Dermatology, 139 (7). 1545-1553.e6.

Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kupz, Andreas, Brough, David, Loukas, Alex, Sutherland, Tara E., Allen, Judith E., and Giacomin, Paul R. (2019) Inflammasome-independent role for NLRP3 in controlling innate antihelminth immunity and tissue repair in the lung. Journal of Immunology, 203 (10). 1900640. pp. 2724-2734.

Filbey, Kara J., Camberis, Mali, Chandler, Jodie, Turner, Rufus, Kettle, Anthony J., Eichenberger, Ramon M., Giacomin, Paul, and Le Gros, Graham (2019) Intestinal helminth infection promotes IL-5- and CD4+ T cell-dependent immunity in the lung against migrating parasites. Mucosal Immunology, 11. pp. 352-362.

Andersson, Anne-Marie C., Buldun, Can M., Pattinson, David, Draper, Simon J., and Howarth, Mark (2019) SnoopLigase peptide-peptide conjugation enables modular vaccine assembly. Scientific Reports, 9. 4625.

Owen, David L., Mahmud, Shawn A., Sjaastad, Louisa E., Williams, Jason B., Spanier, Justin A., Simeonov, Dimitre R., Ruscher, Roland, Huang, Weishan, Miller, Corey, Hekim, Can, Jeschkle, Jonathan C., Aggarwal, Praful, Broeckel, Ulrich, LaRue, Rebecca S., Henzler, Christine M., Alegre, Maria-Luisa, Anderson, Mark S., August, Avery, Marson, Alexander, Zheng, Ye, Williams, Calvin B., and Farrar, Michael A. (2019) Thymic regulatory T cells arise via two distinct developmental programs. Nature Immunology, 20. pp. 195-205.

Vanderven, Hillary A., Wragg, Kathleen, Ana-Sosa-Batiz, Fernanda, Kristensen, Anne B., Jegaskanda, Sinthujan, Wheatley, Adam K., Wentworth, Deborah, Wines, Bruce D., Hogarth, P. Mark, Rockman, Steve, Kent, Stephen J., and INSIGHT FLU005 Pilot Study Writing Group (2018) Anti-influenza hyperimmune immunoglobulin enhances Fc-functional antibody immunity during human influenza infection. Journal of Infectious Diseases, 218 (9). pp. 1383-1393.

Vanderven, Hillary A., Jegaskanda, Sinthujan, Wines, Bruce D., Hogarth, P. Mark, Carmuglia, Sarina, Rockman, Steven, Chung, Amy W., and Kent, Stephen J. (2018) Antibody-dependent cellular cytotoxicity responses to seasonal influenza vaccination in older adults. Journal of Infectious Diseases, 217 (1). pp. 12-23.

O’Sullivan, Brendan J., Yekollu, Suman, Ruscher, Roland, Mehdi, Ahmed M., Maradana, Muralidhara Rao, Chidgey, Ann P., and Thomas, Ranjeny (2018) Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice. Frontiers in Immunology, 9. 1092.

Yeo, Lorraine, Woodwyk, Alyssa, Sood, Sanjana, Lorenc, Anna, Eichmann, Martin, Pujol-Autonell, Irma, Melchiotti, Rosella, Slowera, Ania, Fidanis, Efthymios, Dolton, Garry M., Tungatt, Katie, Sewell, Andrew K., Heck, Susanne, Saxena, Alka, Beam, Craig A., and Peakman, Mark (2018) Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes. Journal of Clinical Investigation, 128. pp. 3460-3474.

Fernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F., Ikonomopoulou, Maria P., and UNSPECIFIED (2018) Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4. 19. pp. 1-11.

Tungatt, Katie, Dolton, Garry, Morgan, Sophie B., Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D., Porter, Emily, Szomolay, Barbara, Montoya, Maria, Hammond, John A., Miles, John J., Cole, David K., Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J., Charleston, Bryan, Tchilian, Elma, and Sewell, Andrew K. (2018) Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. PLoS Pathogens, 14 (5). e1007017.

Miles, John, Tan, Mai Ping, Dolton, Garry, Edwards, Emily S.J., Galloway, Sarah A.E., Laugel, Bruno, Clement, Mathew, Makinde, Julia, Ladell, Kristin, Matthews, Katherine, Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne M., Attaf, Meriem, Lissina, Anya, Ager, Ann, Gallimore, Awen, Rizkallah, Pierre J., Grass, Stephanie, Rossjohn, Jamie, Burrows, Scott, Cole, David K., Price, David A., and Sewell, Andrew K. (2018) Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation, 128 (4). pp. 1569-1580.

Rius, Cristina, Attaf, Meriem, Tungatt, Katie, Bianchi, Valentina, Legut, Mateusz, Bovay, Amandine, Donia, Marco, Straten, Per thor, Peakman, Mark, Svane, Inge Marie, Ott, Sascha, Connor, Tom, Szomolay, Barbara, Dolton, Garry, and Sewell, Andrew (2018) Peptide–MHC class I tetramers can fail to detect relevant functional T cell clonotypes and underestimate antigen-reactive T cell populations. Journal of Immunology, 200 (7). pp. 2263-2279.

Nair, Prema M., Starkey, Malcolm R., Haw, Tatt Jhong, Ruscher, Roland, Liu, Gang, Maradana, Muralidhara R., Thomas, Ranjeny, O’Sullivan, Brendan J., and Hansbro, Philip M. (2018) RelB-Deficient dendritic cells promote the development of spontaneous allergic airway inflammation. American Journal of Respiratory Cell and Molecular Biology, 58 (3). pp. 352-365.

Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., Mclaren, James E., Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A., Rhijn, Ildiko Van, Moody, D. Branch, and Rossjohn, Jamie (2018) T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology, 19. pp. 397-406.

Snape, Natale, Li, Dongshe, Wei, Ting, Jin, Hongping, Lor, Mary, Rawle, Daniel J., Spann, Kirsten M., and Harrich, David (2018) The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production. Virology Journal, 15. 182.

Bangaru, Sandhya, Zhang, Heng, Gilchuk, Iuliia M., Voss, Thomas G., Irving, Ryan P., Gilchuk, Pavlo, Matta, Pranathi, Zhu, Xueyong, Lang, Shanshan, Nieusma, Travis, Richt, Juergen A., Albrecht, Randy A., Vanderven, Hillary A., Bombardi, Robin, Kent, Stephen J., Ward, Andrew B., Wilson, Ian A., and Crowe, James E. (2018) A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nature Communications, 9. 2669.

Bouchery, Tiffany, Filbey, Kara, Shepherd, Amy, Chandler, Jodie, Patel, Deepa, Schmidt, Alfonso, Camberis, Mali, Peignier, Adeline, Smith, Adam A.T., Johnston, Karen, Painter, Gavin, Pearson, Mark, Giacomin, Paul, Loukas, Alex, Bottazzi, Maria-Elena, Hotez, Peter, and LeGros, Graham (2018) A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathogens, 14 (3).

Masson, Jesse J.R., Murphy, Andrew J., Lee, Man K.S., Ostrowski, Matias, Crowe, Suzanne M., and Palmer, Clovis S. (2017) Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy. PLoS ONE, 12 (8). e0183931.

Burel, Julie G., Apte, Simon H., Groves, Penny L., Boyle, Michelle J., Langer, Christine, Beeson, James G., McCarthy, James S., and Doolan, Denise L. (2017) Dichotomous miR expression and immune responses following primary blood-stage malaria. JCI Insight, 2 (15). e93434. pp. 1-18.

Vanderven, Hillary A., Jegaskanda, Sinthujan, Wheatley, Adam K., and Kent, Stephen J. (2017) Antibody-dependent cellular cytotoxicity and influenza virus. Current Opinion in Virology, 22. pp. 89-96.

Ruscher, Roland, Kummer, Rebecca L., Lee, You Jeong, Jameson, Stephen C., and Hogquist, Kristin A. (2017) CD8aa intraepithelial lymphocytes arise from two main thymic precursors. Nature Immunology, 18 (7). pp. 771-779.

Woodberry, Tonia, Loughland, Jessica R., Minigo, Gabriela, Burel, Julie G., Amante, Fiona H., Piera, Kim A., McNeil, Yvette, Yeo, Tsin W., Good, Michael F., Doolan, Denise L., Engwerda, Christian R., McCarthy, James S., and Anstey, Nicholas M. (2017) Early immune regulatory changes in a primary controlled human Plasmodium vivax infection: CD1C + myeloid dendritic cell maturation arrest, induction of the kynurenine pathway, and regulatory T cell activation. Infection and Immunity, 85 (6). e00986-16. e00986-16.

Vanderven, Hillary A., Liu, Lu, Ana-Sosa-Batiz, Fernanda, Nguyen, Thi H.O., Wan, Yanmin, Wines, Bruce, Hogarth, P. Mark, Tilmanis, Danielle, Reynaldi, Arnold, Parsons, Matthew S., Hurt, Aeron C., Davenport, Miles P., Kotsimbos, Tom, Cheng, Allen C., Kedzierska, Katherine, Zhang, Xiaoyan, Xu, Jianqing, and Kent, Stephen J. (2017) Fc functional antibodies in humans with severe H7N9 and seasonal influenza. JCI Insight, 2 (13). e92750. pp. 1-15.

Jegaskanda, Sinthujan, Vanderven, Hillary A., Wheatley, Adam K., and Kent, Stephen J. (2017) Fc or not Fc; that is the question: antibody Fc-receptor interactions are key to universal influenza vaccine design. Human Vaccines & Immunotherapeutics, 13 (6). pp. 1288-1296.

Baturcam, E., Snape, N., Yeo, T.H., Schagen, J., Thomas, E., Logan, J., Galbraith, S., Collinson, N., Phipps, S., Fantino, E., Sly, P.D., and Spann, K.M. (2017) Human metapneumovirus impairs apoptosis of nasal epithelial cells in asthma via HSP70. Journal of Innate Immunity, 9 (1). pp. 52-64.

Hill, Danika L., Schofield, Louis, and Wilson, Danny W. (2017) IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development. International Journal for Parasitology, 47 (10-11). pp. 585-595.

Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A., Cheng, Lesley, Abou Karam, Paula, Sampaio, Natalia G., Penington, Jocelyn Sistema, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J., Sharples, Robyn A., Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S., Papenfuss, Anthony T., Eriksson, Emily M., Gerlic, Motti, Hill, Andrew, Bowie, Andrew G., and Regev-Rudzki, Neta (2017) Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors. Nature Communications, 8. 1985.

Schussek, Sophie, Trieu, Angela, Apte, Simon h., Sidney, John, Sette, Alessandro, and Doolan, Denise L. (2017) Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses. Scientific Reports, 7. 15053.

Loughland, Jessica R., Minigo, Gabriela, Sarovich, Derek S., Field, Matt, Tipping, Peta E., Montes de Oca, Marcela, Piera, Kim A., Amante, Fiona H., Barber, Bridget E., Grigg, Matthew J., William, Timothy, Good, Michael F., Doolan, Denise L., Engwerda, Christian R., Anstey, Nicholas M., McCarthy, James S., and Woodberry, Tonia (2017) Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation. Scientific Reports, 7 (2596). pp. 1-11.

Obaldia, Nicanor III, Stockelman, Michael G., Otero, William, Cockrill, Jennifer A., Ganeshan, Harini, Abot, Esteban N., Zhang, Jianfeng, Limbach, Keith, Charoenvit, Yupin, Doolan, Denise L., Tang, De-chu C., and Richie, Thomas L. (2017) A Plasmodium vivax Plasmid DNA- and adenovirus-vectored malaria vaccine encoding blood-stage antigens AMA1 and MSP1 42 in a prime/boost heterologous immunization regimen partially protects Aotus monkeys against blood-stage challenge. Clinical and Vaccine Immunology, 24 (4). e00539. pp. 1-16.

Burel, Julie G., Apte, Simon H., Groves, Penny L., McCarthy, James S., and Doolan, Denise L. (2017) Polyfunctional and IFN-γ monofunctional human CD4+ T cell populations are molecularly distinct. JCI Insight, 2 (3). e87499. pp. 1-12.

Bruder, Joseph T., Chen, Ping, Ekberg, Greg, Smith, Emily C., Lazarski, Christopher A., Myers, Bennett A., Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas, King, C. Richter, Aguiar, Joao C., Doolan, Denise L., and Brough, Douglas E. (2017) Profiling the targets of protective CD8(+) T cell responses to infection. Molecular Therapy: methods & clinical development, 7. pp. 20-31.

Schofield, Louis, Ioannidis, Lisa J., Karl, Stephan, Robinson, Leanne J., Tan, Qiao Y., Poole, Daniel P., Betuela, Inoni, Hill, Danika L., Siba, Peter M., Hansen, Diana S., Mueller, Ivo, and Eriksson, Emily M/ (2017) Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of gamma delta T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea. BMC Medicine, 15. 114.

Bryan, Donna, Silva, Nilupa, Rigsby, Peter, Dougall, Thomas, Corran, Patrick, Bowyer, Paul W., Ho, Mei Mei, and Collaborative Study Group including Denise Doolan (2017) The establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum. Malaria Journal, 16 (1). 314. pp. 1-10.

De Sousa, Karina P., and Doolan, Denise L. (2016) Immunomics: a 21st century approach to vaccine development for complex pathogens. Parasitology, 143 (2). pp. 236-244.

Apte, Simon H., Stephenson, Rachel J., Simerska, Pavla, Groves, Penny L., Aljohani, Salwa, Eskandari, Sharareh, Toth, Istvan, and Doolan, Denise L. (2016) Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8⁺ T-cell responses. Nanomedicine, 11 (2). pp. 137-152.

Burel, Julie G., Apte, Simon H., and Doolan, Denise L. (2016) Systems approaches towards molecular profiling of human immunity. Trends in Immunology, 37 (1). pp. 53-67.

Kristensen, Anne B., Lay, William N., Ana-Sosa-Batiz, Fernanda, Vanderven, Hillary A., Madhavi, Vijaya, Laurie, Karen L., Carolan, Louise, Wines, Bruce D., Hogarth, Mark, Wheatley, Adam K., and Kent, Stephen J. (2016) Antibody responses with Fc-mediated functions after vaccination of HIV-infected subjects with trivalent influenza vaccine. Journal of Virology, 90 (12). pp. 5724-5734.

Raja, Amber I., Cai, Yeping, Reiman, Jennifer M., Groves, Penny, Chakravarty, Sumana, McPhun, Virginia, Doolan, Denise L., Cockburn, Ian, Hoffman, Stephen L., Stanisic, Danielle I., and Good, Michael F. (2016) Chemically attenuated blood-stage Plasmodium yoelii parasites induce long-lived and strain-transcending protection. Infection and Immunity, 84 (8). pp. 2274-2288.

Lovelace, Michael D., Varney, Bianca, Sundaram, Gayathri, Franco, Nunzio F., Ng, Mei Li, Pai, Saparna, Lim, Chai K., Guillemin, Gilles J., and Brew, Bruce J. (2016) Current evidence for a role of the kynurenine pathway of tryptophan metabolism in multiple sclerosis. Frontiers in Immunology, 7. 246. pp. 1-22.

Skinner-Adams, Tina S., Sumanadasa, Subathdrage D.M., Fisher, Gillian M., Davis, Rohan A., Doolan, Denise L., and Andrews, Katherine T. (2016) Defining the targets of antiparasitic compounds. Drug Discovery Today, 21 (5). pp. 725-739.

Wines, Bruce D., Vanderven, Hillary A., Esparon, Sandra E., Kristensen, Anne B., Kent, Stephen J., and Hogarth, P. Mark (2016) Dimeric FcγR ectodomains as probes of the Fc receptor function of anti-influenza virus IgG. Journal of Immunology, 197 (4). pp. 1507-1516.

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yanqing, Nicovich, Philip R., Bridgeman, John S., Cohnen, Andre, Benzing, Carola, Gao, Yijun, Tungatt, Katie, Dolton, Garry, Sewell, Andrew K., Price, David A., Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jeremy, Rossjohn, Jamie, and Gaus, Katharina (2016) Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences of the United States of America, 113 (44). E5454-E5463.

Ana-Sosa-Batiz, Fernanda, Vanderven, Hillary, Jegaskanda, Sinthujan, Johnston, Angus, Rockman, Steven, Laurie, Karen, Barr, Ian, Reading, Patrick, Lichtfuss, Marit, and Kent, Stephen J. (2016) Influenza-specific antibody-dependent phagocytosis. PLoS ONE, 11 (4). e0154461.

Proietti, Carla, Zakrzewski , Martha , Watkins, Thomas S., Berger, Bernard, Hasan, Shihab, Ratnatunga, Champa N., Brion, Marie-Jo, Crompton, Peter D., Miles, John J., Doolan, Denise L., and Krause, Lutz (2016) Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) web-server. Scientific Reports, 6. 38178. pp. 1-15.

Hickey, Bradley W., Lumsden, Joanne M., Reyes, Sharina, Sedegah, Martha, Hollingdale, Michael R., Freilich, Daniel A., Luke, Thomas C., Charoenvit, Yupin, Goh, Lucy M., Berzins, Mara P., Bebris, Lolita, Sacci Jr., John B., De La Vega, Patricia, Wang, Ruobing, Ganeshan, Harini, Abot, Esteban N., Carucci, Daniel J., Doolan, Denise L., Brice, Gary T., Kumar, Anita, Aguiar, Joao, Nutman, Thomas B., Leitman, Susan F., Hoffman, Stephen L., Epstein, Judith E., and Richie, Thomas L. (2016) Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malaria Journal, 15 (377). pp. 1-18.

Parsons, Matthew S., Richard, Jonathan, Lee, Wen Shi, Vanderven, Hillary, Grant, Michael D., Finzi, Andrés, and Kent, Stephen J. (2016) NKG2D acts as a co-receptor for natural killer cell-mediated anti-HIV-1 antibody-dependent cellular cytotoxicity. AIDS Research and Human Retroviruses, 32 (10-11). pp. 1089-1096.

Burel, Julie G., Apte, Simon H., McCarthy, James S., and Doolan, Denise L. (2016) Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+ T cell population with cytotoxic potential. PLoS Neglected Tropical Diseases, 10 (12). e0005031. pp. 1-11.

Loughland, Jessica R., Minigo, Gabriela, Burel, Julie, Tipping, Peta E., Piera, Kim A., Amante, Fiona H., Engwerda, Christian Rl, Good, Michael F., Doolan, Denise L., Anstey, Nicholas M., McCarthy, James S., and Woodberry, Tonia (2016) Profoundly reduced CD1c+myeloid dendritic cell HLA-DR and CD86 expression and increased tumor necrosis factor production in experimental human blood-stage malaria infection. Infection and Immunity, 84 (5). pp. 1403-1412.

Burel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kerenaftali, McCarthy, James S., and Doolan, Denise L. (2016) Reduced plasmodium parasite burden associates with CD38(+) CD4(+) T cells displaying cytolytic potential and impaired IFN-gamma production. PLoS Pathogens, 12 (9). pp. 1-22.

Sedaghat, Bita, Stephenson, Rachel J., Giddam, Ashwini Kumar, Eskandari, Sharareh, Apte, Simon H., Pattinson, David, Doolan, Denise L., and Toth, Istvan (2016) Synthesis of mannosylated lipopeptides with receptor targeting properties. Bioconjugate Chemistry, 27 (3). pp. 533-548.

de Oca, Marcela Montes, Kumar, Rajiv, Rivera, Fabian de Labastida, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Boyle, Glen M., Price, Ric N., Anstey, Nicholas M., Loughland, Jessica R., Burel, Julie, Doolan, Denise, Haque, Ashraful, McCarthy, James S., and Engwerda, Christian R. (2016) Type I interferons regulate immune responses in humans with blood-stage Plasmodium falciparum infection. Cell Reports, 17 (2). pp. 399-412.

Vanderven, Hillary A., Ana-Sosa-Batiz, Fernanda, Jegaskanda, Sinthujan, Rockman, Steven, Laurie, Karen, Barr, Ian, Chen, Weisan, Wines, Bruce, Hogarth, P. Mark, Lambe, Teresa, Gilbert, Sarah C., Parsons, Matthew S., and Kent, Stephen J. (2016) What lies beneath: antibody dependent natural killer cell activation by antibodies to internal influenza virus proteins. EBioMedicine, 8. pp. 277-290.

Gupta, Shishir K., Srivastava, Mugdha, Akhoon, Bashir A., Smita, Suchi, Schmitz, Ulf, Wolkenhauer, Olaf, Vera, Julio, and Gupta, Shailendra (2011) Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase. Infection, Genetics and Evolution, 11 (2). pp. 308-319.

O'Sullivan, Brendan, Pai, Saparna, Street, Shayna, Macdonald, Kelli, Gerondakis, Steve, Hill, Geoffrey, and Thomas, Ranjeny (2010) Autoreactive T Cells Escaping Thymic Deletion in REL-B Deficient Mice Depend on Dendritic Cell-encoded REL-B for Control of Autoimmunity. Clinical Immunology, 135. S134-S135.

Book Chapter

Lelliot, Emily J., Ramsbottom, Kelly M., Dowling, Mark R., Shewbrey, Carolyn, Noori, Tahereh, Kearney, Conor J., Michie, Jessica, Parish, Ian A., Jordan, Margaret A., Baxter, Alan G., Young, Niel D., Brennan, Amelia J., and Oliaro, Jane (2023) NKG7 Enhances CD8+ T cell synapse efficiency to limit inflammation. In: Baldari, Cosima T., Valitutti, Salvatore, and Dustin, Michael L, (eds.) Mechanisms of Lymphocyte Mediated Cytotoxicity in Health and Disease. Frontiers, Lausanne, Switzerland, pp. 156-170.

Conference Item

Sikder, Suchandan, Williams, Natasha, Sorenson, Alanna, Alim, Md Abdul, Vidgen, Miranda, Moreland, Nicole J., Rush, Catherine M., Simpson, Scott, Govan, Brenda L., Norton, Robert E., McMillan, David J., Sriprakash, Kadaba S., and Ketheesan, Natkunam (2018) A Paradigm Shift for Rheumatic Heart Disease: Role of Group G Streptococcus. In: Presented at the 15th International Scientific Conference]. From: 15th International Scientific Conference, 12-13 May 2018, Chattogram, Bangladesh.

Sikder, Suchandan, Price, Georgina, Alim, Md A., Gautam, Anil, Simpson, Robert, Rush, Catherine, Govan, Brenda, and Ketheesan, Natukunam (2017) Anti-streptococcal antibodies and T-cells induce heart pathology in Lewis rats following adoptive transfer. In: [Presented at the 20th Lancefield International Symposium on Streptococci and Streptococcal Diseases 2017]. From: 20th Lancefield International Symposium on Streptococci and Streptococcal Diseases 2017, 16-20 October 2017, Fiji.

Sikder, Suchandan, Williams, Natasha, Sorenson, Alanna E., Alim, Md A., Vidgen, Miranda E., Moreland, Nicole J., Rush, Catherine M., Simpson, Robert S., Govan, Brenda L., Norton, Robert E., Cunningham, Madeleine E., McMillan, David J., Sriprakash, Kadaba S., and Ketheesan, Natkunam (2017) Group G streptococcus induces autoimmune mediated carditis in the Lewis rat model of Rheumatic Heart Disease. In: [Presented at the 20th Lancefield International Symposium on Streptococci and Streptococcal Diseases 2017]. From: 20th Lancefield International Symposium on Streptococci and Streptococcal Diseases 2017, 16-20 October 2017, Fiji.

Thesis

Cooper, Martha Maria (2020) Molecular profiling of immunity to infectious disease using human challenge models. PhD thesis, James Cook University.