Bacterial extracellular polysaccharides

Bazaka, Kateryna, Crawford, Russell J., Nazarenko, Evgeny L., and Ivanova, Elena P. (2011) Bacterial extracellular polysaccharides. In: Linke , Dirk, and Goldman, Adrian, (eds.) Bacterial Adhesion: Chemistry, Biology and Physics. Advances in Experimental Medicine and Biology, 715 . Springer, London, UK, pp. 213-226.

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Extracellular polysaccharides are as structurally and functionally diverse as the bacteria that synthesise them. They can be present in many forms, including cell-bound capsular polysaccharides, unbound "slime", and as O-antigen component of lipopolysaccharide, with an equally wide range of biological functions. These include resistance to desiccation, protection against nonspecific and specific host immunity, and adherence. Unsurprisingly then, much effort has been made to catalogue the enormous structural complexity of the extracellular polysaccharides made possible by the wide assortment of available monosaccharide combinations, non-carbohydrate residues, and linkage types, and to elucidate their biosynthesis and export. In addition, the work is driven by the commercial potential of these microbial substances in food, pharmaceutics and biomedical industries. Most recently, bacteria-mediated environmental restoration and bioleaching have been attracting much attention owing to their potential to remediate environmental effluents produced by the mining and metallurgy industries. In spite of technological advances in chemistry, molecular biology and imaging techniques that allowed for considerable expansion of knowledge pertaining to the bacterial surface polysaccharides, current understanding of the mechanisms of synthesis and regulation of extracellular polysaccharides is yet to fully explain their structural intricacy and functional variability.

Item ID: 17318
Item Type: Book Chapter (Research - B1)
ISBN: 978-94-007-0939-3
ISSN: 0065-2598
Date Deposited: 04 Aug 2011 07:07
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110801 Medical Bacteriology @ 50%
10 TECHNOLOGY > 1002 Environmental Biotechnology > 100203 Bioremediation @ 20%
06 BIOLOGICAL SCIENCES > 0605 Microbiology > 060501 Bacteriology @ 30%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 30%
97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 40%
97 EXPANDING KNOWLEDGE > 970110 Expanding Knowledge in Technology @ 30%
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