Genetic variation and atherosclerosis

Biros, Erik, Karan, Mirko, and Golledge, Jonathan (2008) Genetic variation and atherosclerosis. Current Genomics, 9 (1). pp. 29-42.

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DOI: 10.2174/138920208783884856

View at Publisher Website: http://dx.doi.org/10.2174/13892020878388...

Abstract

A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying the importance of inheritance in atherosclerosis are starting to be understood. Genetic variation, such as mutations or common polymorphisms has been shown to be involved in modulation of a range of risk factors, such as plasma lipoprotein levels, inflammation and vascular calcification. This review presents examples of present studies of the role of genetic polymorphism in atherosclerosis.

ID Code:6179
Item Type:Article (Refereed Research - C1)
Keywords:atherosclerosis; genetic polymorphism; risk factors
FoR Codes:11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes:92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
Deposited On:11 Feb 2010 08:38
Last Modified:17 May 2013 00:51
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