Challenges, current status and future perspectives of proteomics in improving understanding, diagnosis and treatment of vascular disease

Moxon, J.V., Padula, M.P., Herbert, B.R., and Golledge, J. (2009) Challenges, current status and future perspectives of proteomics in improving understanding, diagnosis and treatment of vascular disease. European Journal of Vascular and Endovascular Surgery, 38 . pp. 346-355.

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DOI: 10.1016/j.ejvs.2009.05.008

View at Publisher Website: http://dx.doi.org/10.1016/j.ejvs.2009.05...

Abstract

Abstract Technical advances have seen the rapid adoption of genomics and multiplex genetic polymorphism identification to research on vascular diseases. The utilization of proteomics for the study of vascular diseases has been limited by comparison. In this review we outline currently available proteomics techniques, the challenges to using these approaches and modifications which may improve the utilization of proteomics in the study of vascular diseases. ª 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

ID Code:5349
Item Type:Article (Refereed Research - C1)
Keywords:proteomics; mass spectrometry; secretome; vascular medicine
FoR Codes:11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes:92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
Deposited On:02 Oct 2009 09:15
Last Modified:10 Jun 2013 00:45
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