New heteroditopic, linked macrocyclic systems derived from selectively protected N2S2-, N3O2- and N4-donor macrocycles

Abstract

The use of selectively tert-butoxycarbonyl protected derivatives of 1,9-dithia-5,13-diazacyclohexadecane 1, 1,7-dithia-4,11-diazacyclotetradecane 2, 1,4,8,11-tetraazacyclotetradecane 3 and 2,5-dioxa-8,11,14-triaza-1,6(1,2)-dibenzenacyclopentadecaphane 4 has enabled the efficient synthesis of new linked heteroditopic macrocyclic systems incorporating combinations of N₂S₂- and N₄- or N₃O₂-donor sites. Incorporation of two types of binding sites in the respective products makes them suitable candidates for the synthesis of a range of mixed-metal, di- and oligo-nuclear metal complexes.