Dissecting genetic mechanisms conferring susceptibility to autoimmune diseases
Silveira, Pablo A., Jordan, Margaret A., and Baxter, Alan G. (1999) Dissecting genetic mechanisms conferring susceptibility to autoimmune diseases. Current Allergy and Clinical Immunology, 12 . pp. 10-16.
|PDF (Published Version) - Repository staff only - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader|
[Extract] Autoimmunity is defined as a specific immune response directed against one or more self antigens that occurs as a result of the failure or breakdown in the mechanisms responsible for maintaining immunological tolerance. Although autoimmunity is not necessarily destructive, in a small proportion of individuals, it can lead to pathological tissue damage. Depending on the target tissue of the autoimmune attack, a variety of autoimmune diseases can ensue which differ greatly in their clinical presentation.
|Item Type:||Article (Refereed Research - C1)|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110703 Autoimmunity @ 100%|
|SEO Codes:||92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%|
|Deposited On:||07 Jun 2012 10:57|
|Last Modified:||07 Jun 2012 18:02|
Last 12 Months: 0
Repository Staff Only: item control page