Advanced drug-delivery systems
Glass, Beverley D., Haywood, Alison, Khar, Roop K., and Garg, Sanjay (2011) Advanced drug-delivery systems. In: MCQs in Pharmaceutical Science and Technology. Pharmaceutical Press, London, UK, pp. 171-218.
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[Extract] Over the past decade, despite the importance of the biotechnology industry and increasing expenditure in research and development, there have been only a limited number of drugs originating from large pharmaceutical companies. The pharmaceutical industry has turned its attention to advanced drug-delivery systems such as pulmonary, transdermal, rectal and vaginal, proteins and gene, nasal, buccal and opthalmic, parenteral, total parenteral nutrition (TPN) and aerosol delivery, and these are the focus of this test. The philosophy behind these delivery systems is to increase therapeutic effects while decreasing toxicity by increasing the drug in the vicinity of the target cells and reducing drug exposure to non-target cells. The benefits of this approach include patient adherence and acceptance of their medications, improved outcomes and a reduction in adverse effects. The medications are such that they may be given to outpatients, resulting in a reduction in the overall use of medical resources.
|Item Type:||Book Chapter (Teaching Material)|
|Keywords:||transdermal, aerosols, pulmonary, nasal, buccal|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified @ 100%|
|SEO Codes:||92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%|
|Deposited On:||24 Sep 2012 15:25|
|Last Modified:||24 Sep 2012 15:25|
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