Problems with the use of a lateral flow assay in the serodiagnosis of brucellosis

Abstract

[Extract] Currently Brucella suis is the only causative agent of endemic brucellosis in Australia. The incidence of human brucellosis in Australia is 0.2 per 100 000. This equates to approximately 40–50 cases each year including occasional imported cases caused by Brucella melitensis. Of the cases reported, 80% occur in Queensland. The clinical manifestations of human brucellosis are protean and non-specific, posing a diagnostic challenge to clinicians. Delay in time to diagnosis and poor management of brucellosis may result in serious, sometimes life-threatening complications. Chronic brucellosis is not uncommon and can have an enormous impact on the patient's physical, mental and occupational health. A recent study in North Queensland has described the clinical and psychological impact of this disease.