Deep microsporidial keratitis after keratoconjunctivitis
Badenoch , Paul R., Coster, Douglas J., Sadlon, Tania A., Klebe, Sonja, Stirling, John W., Jaunzems, Alvis E., and Mazierska, Janina E. (2011) Deep microsporidial keratitis after keratoconjunctivitis. Clinical and Experimental Ophthalmology, 39 (6). pp. 577-580.
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[Extract] Microsporidia are intracellular pathogens of animals andhumans. Although not hyphal, a recent study suggests theyare fungi descended from an ancestral zygomycete. Theyhave a unique method for invading susceptible tissue: an internal coiled tube everts rapidly and sporoplasm moves into the cell as if through a hypodermic needle. In the human eye, microsporidial infection presents as keratoconjunctivitis or stromal keratitis. The former has been reported in HIV+ patients because of Encephalitozoon and in immunocompetent patients because of several genera. Stromal infection is seen in immunocompetent patients and is caused mostly by Vittaforma corneae. We report a case in which keratoconjunctivitis preceded deep stromal infection in a patient with a low neutrophil count.
|Item Type:||Article (Case Study)|
|Keywords:||microsporidium, Vittaforma corneae, cornea, keratitis, rRNA gene|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1113 Ophthalmology and Optometry > 111301 Ophthalmology @ 50%|
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110199 Medical Biochemistry and Metabolomics not elsewhere classified @ 50%
|SEO Codes:||92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920107 Hearing, Vision, Speech and Their Disorders @ 100%|
|Deposited On:||21 Feb 2012 15:25|
|Last Modified:||18 Oct 2013 01:24|
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