The cardiovascular and prognostic significance of the infra-renal aortic diameter
Norman, Paul E., Muller, Juanita, and Golledge, Jonathan (2011) The cardiovascular and prognostic significance of the infra-renal aortic diameter. Journal of Vascular Surgery, 54 (6). 1817-1820.
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The normal aortic diameter in adults usually ranges from 16 to 18 mm in women and 19 to 21 mm in men. Individuals with diameters outside this range seem to be at increased risk of other cardiovascular disease. There is a graded association between increasing aortic diameter and both cardiovascular mortality and peripheral arterial disease. The magnitude of increased risk of cardiovascular death seems to be about 4% to 6% per mm increase over a diameter of about 23 mm. To a lesser extent, these outcomes are also increased in individuals with aortic diameters below the normal range. While the threshold of 3 cm is useful in the diagnosis of abdominal aortic aneurysm (AAA), it is arbitrary in terms of the vascular biology and pathophysiology of the abdominal aorta. This review examines the risk factors for aortic enlargement and the cardiovascular implications of this enlargement in patients with and without AAAs. The mechanisms underlying the association between aortic diameter and cardiovascular risk and the relevance to screening are also discussed.
|Item Type:||Article (Refereed Research - C1)|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%|
|SEO Codes:||92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%|
|Deposited On:||07 Dec 2011 16:39|
|Last Modified:||26 May 2013 01:36|
Last 12 Months: 0
|Citation Counts with External Providers:||Web of Science: 2|
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