Canyon, Deon V., Heukelbach, Jorg, Shaalan, Essam S., and Speare, Richard (2010) Piperonyl butoxide. In: Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. Hodder Arnold, London, UK, pp. 2306-2309.
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[Extract] Piperonyl butoxide (PBO) contains the methylenedioxyphenyl moiety, a molecule found in sesame oil and later named sesamin, and thus is classified as a member of the methylenedioxyphenyl group of chemicals. In 1947, it was semisynthesized from safrole, the principal component of camphor oil (Knowles, 1991; Tozzi, 1998). Its molecular formula is C19H300S; it has a molecular weight of 338.4 g/mol. The chemical structure is shown in Figure 205.1. PBO is a colorless to pale-yellow liquid and is moderately stable in that it is resistant to hydrolysis, oxidation, and exposure to sunlight (Kidd and James, 1994). Manufacturers include MGK and Prentiss and Johnsan (Tozzi, 1998). Since its discovery, and since pesticide resistance has emerged as a problem, PBO has been frequently used as an insecticide synergist, in over 1700 insecticides (USEPA, 2002).
|Item Type:||Book Chapter (Teaching Material)|
This chapter is within Part 7 Agents Active Against Ectoparasites
|Keywords:||antibiotic, piperonyl butoxide|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 100%|
|SEO Codes:||92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920499 Public Health (excl. Specific Population Health) not elsewhere classified @ 100%|
|Deposited On:||05 May 2011 10:12|
|Last Modified:||05 May 2011 18:03|
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