Risk factors for colonic perforation after screening computed tomographic colonography: a multicentre analysis and review of the literature
Atalla, Mohamed Anwar, Rozen, Warren M., Niewiadomski, Olga Dorota, Croxford, Matthew A., Cheung, Wa, and Ho, Yik-Hong (2010) Risk factors for colonic perforation after screening computed tomographic colonography: a multicentre analysis and review of the literature. Journal of Medical Screening, 17 (2). pp. 99-102.
|PDF (Published Version) - Repository staff only - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader|
View at Publisher Website: http://dx.doi.org/10.1258/jms.2010.01004...
Background: Computed tomographic (CT) colonography (or ‘virtual’ colonoscopy) has become an increasingly popular tool for colorectal cancer screening. Colonic perforation, an uncommon complication, is a risk that has not been widely reported.
Methods: A systematic review of the literature was undertaken to identify all reported risk factors for colonic perforation following CT colonography. In addition, a retrospective multicentre study was undertaken, evaluating all CT colonographies in 10 major metropolitan tertiary referral centres. All colonic perforations were assessed for risk factors.
Results: A range of ‘patient’-related and ‘procedure’-related risk factors were identified in the literature. Among 3458 CT colonographies, there were two cases of colonic perforation contributing to an incidence of perforation of 0.06%. There was no statistical correlation between the incidence of perforation and institutional experience (P = 0.66). Risk factors common to both cases and the literature included age, recent colonoscopy and manual colonic insufflation. Diverticular disease and recent colonic biopsy were also notable factors.
Conclusion: There is a small but real risk of perforation following CT colonography. Patient selection and preventative procedural measures may reduce this risk. The importance of the consent process is emphasized.
|Item Type:||Article (Refereed Research - C1)|
|Keywords:||colonic perforation; colonography|
|FoR Codes:||11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110323 Surgery @ 50%|
11 MEDICAL AND HEALTH SCIENCES > 1112 Oncology and Carcinogenesis > 111204 Cancer Therapy (excl Chemotherapy and Radiation Therapy) @ 50%
|SEO Codes:||92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920102 Cancer and Related Disorders @ 100%|
|Deposited On:||27 Aug 2010 08:44|
|Last Modified:||18 Jun 2013 01:17|
Last 12 Months: 0
|Citation Counts with External Providers:||Web of Science: 0|
Repository Staff Only: item control page